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AME entered an official partnership with Publons to enhance wide-ranging recognition for reviewers

AME Publishing Company entered an official partnership with Publons, a product of Clarivate Analytic Company (which owns Web of Science, EndNote, ScholarOne, among many others), as of April 2020. Around 60 AME journals’ peer review systems are now integrated seamlessly into the Publons platform (https://publons.com/about/home). The partnership was done to recognize our expert peer reviewers spontaneously for their review contribution.

Non-coding RNA Investigation (NCRI) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Non-coding RNA Investigation (NCRI) is among the list of COPE membership.

Application of the CARE Guideline as reporting standard in Non-coding RNA Investigation

Non-coding RNA Investigation welcomes case reports which are supposed to report new observations of diseases, clinical findings or novel/unique treatment outcomes relevant to practitioners in the fields of medicine.

Implementation of transparent peer review at Non-coding RNA Investigation (NCRI)

With a commitment to openness and accountability, and to increase the level of transparency throughout our peer review process, our editorial office has decided to implement a transparent peer review process as an option for all manuscripts submitted to NCRI from March 19, 2020.

Regulatory roles of small RNAs in prokaryotes: parallels and contrast with eukaryotic miRNA

Small non-coding RNAs continue to be identified that regulate the processes of translation and transcription in prokaryotes. A variety of regulatory mechanisms have been characterized by these regulatory RNAs that occur by complementary base pairing between the small regulatory RNA (sreRNA) and a target mRNA, including transcription attenuation, translation inhibition, translation activation, and mRNA protection.

MicroRNA regulation of CD8+ T cell responses

This review focuses on the regulatory mechanisms that govern CD8+ T cell fate and function within immune responses, emphasizing the roles of miRNAs in controlling or modulating these mechanisms. Additionally, the authors provide commentary on emergent principles of miRNA regulation.

The role of small and long non-coding RNAs in cardiac pathologies

Cardiovascular disorders (CVDs) still remain the leading cause of death worldwide. The current lack of therapeutic approaches that efficiently improve CVD quality of care and prevent the development of life-threatening complications, prompted the scientific community to continue a deeper investigation of the molecular mechanisms driving the onset and progression of these pathologies. In this context, non-coding RNAs (ncRNAs) were demonstrated to be involved in the onset of different forms of CVDs.

Bone marrow-derived cell mobilization with suppression of CXCR4 mediated by exosomes carrying myocardial microRNAs for repair of the infarcted heart

Blockade of CXCR4 increases mobilization of BM-derived cells in peripheral blood and their incorporation into ischemic myocardial tissue. In this context, Cheng et al. showed that circulating myocardial microRNAs carried in exosomes can selectively transfer to BM and mediate the BM-derived cells transmitted to the peripheral circulation by downregulation of CXCR4.

Circular RNA: closing the loop for miRNA translation to patients

MiRNAs (miRs) have been widely studied in all aspects of medicine. However, the method by which miR-mediated functions are negatively regulated remains an unresolved question. The identification of circular RNA (circRNA) has been shown to act as sponges for miRs. The paper by Zhang et al., shows circDYM serving as a sponge for miR-9.

Trends of non-coding RNAs research in acute rejection after kidney transplantation

Understanding of non-coding RNAs’ (ncRNAs) function and the existence of a highly regulated interplay between mRNA/miRNAs/lncRNAs in allograft rejection has gained the attention of research groups to explore different expression patterns of ncRNAs in the field of organ transplantation.

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Editorial Commentary

Mitochondrial targeted nanoparticle encapsulated circRNA attenuates NASH: one step closer to the therapeutic application of circRNA in liver diseases

Taihua Yang, Bing Li, Zhen Dai

Non-coding RNA Investigation

2021;

(10 April 2021)

PDF Full Text (881) COI Form Open Access

Editorial Commentary

Exercise prevents cardiovascular dysfunctions in diabetes through miRNAs modulation

Saveria Femminò, Pasquale Pagliaro

Non-coding RNA Investigation

2021;

(10 April 2021)

PDF Full Text (763) COI Form Open Access

Editorial Commentary

A microRNA prevents resistance to targeted therapy in chronic myeloid leukemia

Arevik Ghazaryan, Charles B. Goodwin, Ryan M. O’Connell

Non-coding RNA Investigation

2020;

(30 December 2020)

PDF Full Text (1663) COI Form Open Access

Editorial Commentary

High-precision screen to identify lncRNAs governing specific mitotic stages

Dimitrios Tsitsipatis, Battulga Amarbat, Myriam Gorospe, Kotb Abdelmohsen

Non-coding RNA Investigation

2020;

(30 December 2020)

PDF Full Text (935) COI Form Open Access

Editorial Commentary

Krüppel-like factor 4-mediated smooth muscle cell phenotype switching to a galectin-3 positive subclass is a detrimental event in the pathogenesis of atherosclerotic cardiovascular disease

Menno Hoekstra

Non-coding RNA Investigation

2020;

(30 December 2020)

PDF Full Text (948) COI Form Open Access

Editorial Commentary

MiR-129-5p: a novel therapeutic target for amyotrophic lateral sclerosis?

Zachary C. E. Hawley, Danae Campos-Melo, Michael J. Strong

Non-coding RNA Investigation

2020;

(30 December 2020)

PDF Full Text (1162) COI Form Open Access

Editorial Commentary

Can long non-coding RNAs reveal the hidden code of lung cancer?

Joan J. Castellano, Alfons Navarro

Non-coding RNA Investigation

2020;

(30 June 2020)

PDF Full Text (1536) COI Form Open Access

Editorial Commentary

A new hypoxia-responsive lncRNA in metastatic breast cancer

Juliet D. French, Stacey L. Edwards

Non-coding RNA Investigation

2020;

(30 June 2020)

PDF Full Text (1362) COI Form Open Access

Editorial Commentary

NEAT1 isoform expression in breast cancer

Stacey L. Edwards, Juliet D. French

Non-coding RNA Investigation

2020;

(30 June 2020)

PDF Full Text (1558) COI Form Open Access

Editorial Commentary

Another step forward towards unraveling the biological mechanisms driving breast cancer predisposition: a role for non-coding RNAs

Antoinette Hollestelle

Non-coding RNA Investigation

2020;

(30 June 2020)

PDF Full Text (1384) COI Form Open Access

Editorial Commentary

Towards a universal nomenclature standardization for circular RNAs

Marina C. Costa, Francisco J. Enguita

Non-coding RNA Investigation

2020;

(30 June 2020)

PDF Full Text (1734) COI Form Open Access

Editorial Commentary

Down-regulation of miR-24 in diabetes: a novel insight into the mechanism of diabetic exacerbation of myocardial ischaemia-reperfusion injury

Robert M. Bell, Derek M. Yellon

Non-coding RNA Investigation

2020;

(31 March 2020)

PDF Full Text (1610) COI Form Open Access

News

Application of the CARE guideline as reporting standard in the Non-coding RNA Investigation

Editorial Office

Non-coding RNA Investigation

2019;

(26 November 2019)

PDF Full Text (1441) Open Access

Review Article

Regulatory roles of small RNAs in prokaryotes: parallels and contrast with eukaryotic miRNA

Derrick Watkins, Dev P. Arya

Non-coding RNA Investigation

2019;

(26 November 2019)

PDF Full Text (5878) COI Form Open Access

Editorial Commentary

The exosomes carry new hope for cardiac regeneration

Paolo Madeddu

Non-coding RNA Investigation

2019;

(26 November 2019)

PDF Full Text (1847) COI Form Open Access

Review Article

Non-coding RNAs and drug-induced liver injury

Mengxue Sun, Meiyi Song, Fei Wang

Non-coding RNA Investigation

2019;

(09 September 2019)

PDF Full Text (2292) COI Form Open Access

Review Article

The roles of miRNAs in liver diseases

Zhen Dai, Taihua Yang, Guangqi Song

Non-coding RNA Investigation

2019;

(30 August 2019)

PDF Full Text (2680) COI Form Open Access

Review Article

MicroRNA regulation of CD8⁺ T cell responses

John D. Gagnon, K. Mark Ansel

Non-coding RNA Investigation

2019;

(26 August 2019)

PDF Full Text (3176) COI Form Open Access

Editorial

Circulating microRNAs as modifiable diagnostic biomarkers of gestational and transgenerational metabolic risk: can exercise play a role?

Paola Pinto-Hernández, Cristina Tomás-Zapico, Eduardo Iglesias-Gutiérrez

Non-coding RNA Investigation

2019;

(21 August 2019)

PDF Full Text (2192) COI Form Open Access

Editorial Commentary

Exosomal miR-34a: the code for adipocyte-macrophage communication

Xiao Han, Yaqin Zhang

Non-coding RNA Investigation

2019;

(06 June 2019)

PDF Full Text (1930) COI Form Open Access

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Review Article

Long noncoding RNAs and their roles in skeletal muscle fate determination

Mackenzie Hagan, Mi Zhou, Muhammad Ashraf, Il-man Kim, Huabo Su, Neal L. Weintraub, Yaoliang Tang

Editorial

CELF1 regulates gap junction integrity contributing to dilated cardiomyopathy

Danielle A. Jeffrey, Carmen C. Sucharov

Editorial

miRNA-211 stops the clock

Carmit Levy, Tamar Golan, David E. Fisher

Editorial

MicroRNA-146a & hematopoiesis: friend or foe in atherosclerosis

Robert L. Raffai

Editorial

A circular RNA regulator quaking: a novel gold mine to be unfolded in doxorubicin-mediated cardiotoxicity

Tatsuya Aonuma, Ahmed S. Bayoumi, Yaoliang Tang, Il-man Kim

Editorial

How T cells go rogue in the absence of Roquins

Abdalla Akef, Stefan A. Muljo

Editorial

Target RNA-directed microRNA degradation; which controls which?

Mitsuo Kato

Editorial

LncGata6-controlled stemness in regeneration and cancer

Youn-Sang Jung, Moon Jong Kim, Jae-Il Park

Editorial

TWIST1 regulation of circRNA: a novel mechanism to promote epithelial-mesenchymal transition in hepatocellular carcinoma

Zachary A. Yochum, Timothy F. Burns

Editorial

Nuclear export mechanisms of circular RNAs: size does matter

Asfar S. Azmi

Editorial

Multi-leveled suppression of p53 function by HuR lncRNPs

Jen-Hao Yang, Myriam Gorospe

Editorial

circRNA meets gene amplification

Nicholas Manguso, Armando E. Giuliano, Hisashi Tanaka

Editorial

A link between a synonymous SNP and the clinical response to tyrosine kinase inhibitors

Wan-Xin Peng, Le-Tao Fan, Yin-Yuan Mo

Letter to the Editor

Identifying intronic circRNAs: progress and challenges

Amaresh C. Panda, Myriam Gorospe

Correspondence

Cross-communication between fibroblasts and cardiomyocytes

Jae Gyun Oh, Changwon Kho

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Journal Highlight more

Non-coding RNA Investigation is an international, open access, peer-reviewed scientific journal for presenting and discussing frontiers in non-coding RNA, covering all basic, clinical and translational research involved non-coding RNAs and their regulatory roles in health and disease.