A new method for the identification of thousands of circular RNAs

Baptiste Bogard, Claire Francastel, Florent Hubé


Circular RNAs (circRNAs) have recently emerged as a novel class of abundant endogenous non-coding RNAs (ncRNAs) with regulatory potential in mammalian cells. Owing to the difficulty to identify these RNAs through traditional methods dedicated to the analysis of linear RNAs, our knowledge of these intriguing RNA species has remained limited.