%0 Journal Article %T MicroRNA regulation of CD8 + T cell responses %A Gagnon, John D. %A Ansel, K. Mark %J Non-coding RNA Investigation %D 2019 %B 2019 %9 %! MicroRNA regulation of CD8 + T cell responses %K %X MicroRNAs (miRNAs) are a class of short noncoding RNAs that play critical roles in the regulation of a broad range of biological processes. Like transcription factors, miRNAs exert their effects by modulating the expression of networks of genes that operate in common or convergent pathways. CD8 + T cells are critical agents of the adaptive immune system that provide protection from infection and cancer. Here, we review the important roles of miRNAs in the regulation of CD8+ T cell biology and provide perspectives on the broader emerging principles of miRNA function. %U https://ncri.amegroups.org/article/view/5292 %V 3 %P %@ 2522-6673