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Structural basis for assembly and function of the 7SK snRNP complex

   
@article{NCRI4852,
	author = {Aditi N. Borkar and Iván D’Orso},
	title = {Structural basis for assembly and function of the 7SK snRNP complex},
	journal = {Non-coding RNA Investigation},
	volume = {2},
	number = {0},
	year = {2018},
	keywords = {},
	abstract = {RNA plays a central role in the precise control of several biological processes including transcription, translation and DNA replication. As such, correct function of RNA-mediated processes is vital for maintaining cell homeostasis thereby avoiding malignancy. The recent structure of human LARP7 and its binding site on 7SK RNA by Feigon and co-workers (1) reveals molecular details into how this protein-RNA interaction contributes to 7SK RNA recognition and provides insights into the assembly of the 7SK small nuclear ribonucleoprotein (snRNP) complex for correct transcriptional control.},
	issn = {2522-6673},	url = {https://ncri.amegroups.org/article/view/4852}
}