Beyond brown adipogenesis the inheritance of imprinted H19

High-calorie food and sedentary living style give rise to the contemporary pandemics of overweight and obesity. Currently, nearly one-third of population in the world are either overweight or obese, and this number is expected to continuously increase in next decades. Obesity not only compromises glucose tolerance and insulin sensitivity, but also links to serious diseases, including type 2 diabetes, non-alcoholic fatty liver, cardiovascular diseases, and several types of cancers (1).