Article Abstract

A novel miR-205-mediated ERRFI1/EGFR regulatory pathway in MET-addicted cancer cells: emerging biomarkers for secondary resistance

Authors: Carlos Pedraz-Valdunciel, Martyna Filipska, Imane Chaib, Rafael Rosell

Abstract

In the last two decades, many efforts have been made towards the development of innovative and targeted therapeutic approaches for cancer treatment. Nonetheless, in contrast to the several hallmarks achieved in recent years, drug resistance to cancer therapies has arisen as the real challenge.