Article Abstract

miR-100 and miR-125b regulate epithelial-mesenchymal transition and drug resistance in tumors

Authors: Viviana Vallacchi, Monica Rodolfo

Abstract

MIR100HG is a miRNA-host long non-coding RNA (lncRNA) gene encoding in its third intron for pre-miR-100, pre-miR-125b-1 and pre-let-7a-2 giving rise to mature miR-100, miR-125b and let-7a after processing. LncRNAs are transcripts longer than 200 nucleotides that can be capped, spliced, and polyadenylated but are not translated into proteins.