Article Abstract

A miR-20a/MAPK1 connection widens therapeutic perspectives in breast cancer

Authors: Lucas Philippe, Philippe Georgel

Abstract

Over the past decade, microRNAs (miRNAs) have emerged as major players enabling accurate gene expression and regulation. As such, they participate in basic cellular processes, like apoptosis and proliferation which are often deregulated in cancer cells (1). This feature has been largely documented in the case of the miR-17~92 cluster, the overexpression of which is a key event in oncogenesis (2).