Article Abstract

Lactosylated arginine-dehydrophenylalanine nanoparticles increase the selective delivery of miR-199a-3p to liver tumor cells enhancing antitumoral activity

Authors: Fabiola Milosa, Francesca Faillaci, Rosina Critelli, Erica Villa

Abstract

MicroRNAs (miRNAs) are small, non-coding, single-stranded RNAs of about 22 nucleotides in length. They are post-transcriptional modulators of gene expression that act predominantly through the degradation of their target mRNAs.