Article Abstract

MicroRNA-146a & hematopoiesis: friend or foe in atherosclerosis

Authors: Robert L. Raffai

Abstract

Atherosclerosis is recognized as a chronic inflammatory disease of the vascular wall, resulting in the narrowing of blood vessels caused by the growth of lipid-rich lesions. Immune cells of all sorts have been identified in atherosclerotic lesions and their individual contributions to the pathogenesis of atherosclerosis continue to be an active topic of cardiovascular disease research. Hyperlipidemia has long been recognized as a source of inflammation that drives atherosclerosis (1).