Article Abstract

Identifying intronic circRNAs: progress and challenges

Authors: Amaresh C. Panda, Myriam Gorospe

Abstract

In an insightful editorial (1), Bogard and colleagues discussed a recent publication from our laboratory describing the method ‘RNase R treatment followed by Polyadenylation and poly(A)+ RNA Depletion’ (RPAD) to isolate highly enriched circular RNAs (circRNAs) from heterogeneous total RNA pools (2).